Selenoprotein P (SELENOP)

Homo sapiens — UniProt P49908

Gene: SELENOPHomo sapiensSwissProt reviewed

About Selenoprotein P

Selenoprotein P (SELENOP) is a protein from Homo sapiens identified by UniProt accession P49908, 381 residues long. MolForge cross-references it against 0 known binders and 299 disease associations.

Target properties

Protein nameSelenoprotein P
UniProt accessionP49908
GeneSELENOP
OrganismHomo sapiens
Length381 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (299)

Diseases linked to this target (Open Targets).

  • IGF-1 measurement · score 0.31
  • lean body mass · score 0.26
  • blood protein measurement · score 0.26
  • appendicular lean mass · score 0.23
  • serum urea measurement · score 0.20
  • vital capacity · score 0.16
  • body weight · score 0.14
  • longitudinal BMI measurement · score 0.11
  • response to amisulpride · score 0.11
  • whole body water mass · score 0.11

3D Structure

Predicted structure for P49908 is available from the AlphaFold Protein Structure Database.

Amino-acid sequence (381 residues)

MWRSLGLALA LCLLPSGGTE SQDQSSLCKQ PPAWSIRDQD PMLNSNGSVT VVALLQASUY LCILQASKLE DLRVKLKKEG YSNISYIVVN HQGISSRLKY THLKNKVSEH IPVYQQEENQ TDVWTLLNGS KDDFLIYDRC GRLVYHLGLP FSFLTFPYVE EAIKIAYCEK KCGNCSLTTL KDEDFCKRVS LATVDKTVET PSPHYHHEHH HNHGHQHLGS SELSENQQPG APNAPTHPAP PGLHHHHKHK GQHRQGHPEN RDMPASEDLQ DLQKKLCRKR CINQLLCKLP TDSELAPRSU CCHCRHLIFE KTGSAITUQC KENLPSLCSU QGLRAEENIT ESCQURLPPA AUQISQQLIP TEASASURUK NQAKKUEUPS N

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Quick facts

UniProtP49908
GeneSELENOP
OrganismHomo sapiens
Length381
Binders0
Diseases299
View on UniProt