About Cathelicidin antimicrobial peptide
Cathelicidin antimicrobial peptide (CAMP) is a protein
from Homo sapiens identified by UniProt accession
P49913, 170 residues long.
MolForge cross-references it against 0 known binders and
435 disease associations.
Target properties
| Protein name | Cathelicidin antimicrobial peptide |
|---|
| UniProt accession | P49913 |
|---|
| Gene | CAMP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 170 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (435)
Diseases linked to this target (Open Targets).
- lung adenocarcinoma · score 0.19
- endometrial cancer · score 0.15
- neoplasm · score 0.11
- Immunodeficiency due to a late component of complements deficiency · score 0.11
- hepatocellular carcinoma · score 0.10
- immunodeficiency 28 · score 0.10
- recurrent Neisseria infections due to factor D deficiency · score 0.09
- Systemic lupus erythematosus · score 0.09
- oral squamous cell carcinoma · score 0.09
- varicella, severe recurrent · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P49913-F1 | alphafold | PREDICTED | 79.98 | — |
Amino-acid sequence (170 residues)
MKTQRDGHSL GRWSLVLLLL GLVMPLAIIA QVLSYKEAVL RAIDGINQRS SDANLYRLLD LDPRPTMDGD PDTPKPVSFT VKETVCPRTT QQSPEDCDFK KDGLVKRCMG TVTLNQARGS FDISCDKDNK RFALLGDFFR KSKEKIGKEF KRIVQRIKDF LRNLVPRTES
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