Guanine nucleotide-binding protein G(I)/G(S)/G(O)…

About Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 (GNG10) is a protein from Homo sapiens identified by UniProt accession P50151, 68 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein name	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
UniProt accession	P50151
Gene	GNG10
Organism	Homo sapiens
Length	68 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (37)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.30
breast adenocarcinoma · score 0.28
gastric adenocarcinoma · score 0.24
lymphocyte:monocyte ratio · score 0.10
monocyte count · score 0.10
liver disease · score 0.07
protein measurement · score 0.05
lymphocyte count · score 0.04
BMI-adjusted waist-hip ratio · score 0.03
testosterone measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P50151-F1	alphafold	PREDICTED	89.10	—

Amino-acid sequence (68 residues)

MSSGASASAL QRLVEQLKLE AGVERIKVSQ AAAELQQYCM QNACKDALLV GVPAGSNPFR EPRSCALL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 (GNG10)