Homeobox protein MOX-2 (MEOX2)

About Homeobox protein MOX-2

Homeobox protein MOX-2 (MEOX2) is a protein from Homo sapiens identified by UniProt accession P50222, 304 residues long. MolForge cross-references it against 0 known binders and 203 disease associations.

Target properties

Protein name	Homeobox protein MOX-2
UniProt accession	P50222
Gene	MEOX2
Organism	Homo sapiens
Length	304 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (203)

Diseases linked to this target (Open Targets).

heel bone mineral density · score 0.50
bone quantitative ultrasound measurement · score 0.47
body height · score 0.44
bone density · score 0.39
FEV/FVC ratio · score 0.31
triglyceride measurement · score 0.29
vital capacity · score 0.29
BMI-adjusted waist circumference · score 0.29
sex hormone-binding globulin measurement · score 0.26
high density lipoprotein cholesterol measurement · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P50222-F1	alphafold	PREDICTED	60.48	—

Amino-acid sequence (304 residues)

MEHPLFGCLR SPHATAQGLH PFSQSSLALH GRSDHMSYPE LSTSSSSCII AGYPNEEGMF ASQHHRGHHH HHHHHHHHHH QQQQHQALQT NWHLPQMSSP PSAARHSLCL QPDSGGPPEL GSSPPVLCSN SSSLGSSTPT GAACAPGDYG RQALSPAEAE KRSGGKRKSD SSDSQEGNYK SEVNSKPRKE RTAFTKEQIR ELEAEFAHHN YLTRLRRYEI AVNLDLTERQ VKVWFQNRRM KWKRVKGGQQ GAAAREKELV NVKKGTLLPS ELSGIGAATL QQTGDSIANE DSHDSDHSSE HAHL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards