Cysteine-rich protein 1 (CRIP1)

About Cysteine-rich protein 1

Cysteine-rich protein 1 (CRIP1) is a protein from Homo sapiens identified by UniProt accession P50238, 77 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

Target properties

Protein name	Cysteine-rich protein 1
UniProt accession	P50238
Gene	CRIP1
Organism	Homo sapiens
Length	77 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (63)

Diseases linked to this target (Open Targets).

heel bone mineral density · score 0.33
body height · score 0.32
lean body mass · score 0.31
fat body mass · score 0.24
calcium measurement · score 0.22
total blood protein measurement · score 0.12
blood protein measurement · score 0.12
serum albumin measurement · score 0.12
neoplasm · score 0.10
diabetes mellitus · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P50238-F1	alphafold	PREDICTED	81.83	—

Amino-acid sequence (77 residues)

MPKCPKCNKE VYFAERVTSL GKDWHRPCLK CEKCGKTLTS GGHAEHEGKP YCNHPCYAAM FGPKGFGRGG AESHTFK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards