About Sulfate transporter
Sulfate transporter (SLC26A2) is a protein
from Homo sapiens identified by UniProt accession
P50443, 739 residues long.
MolForge cross-references it against 0 known binders and
302 disease associations.
Target properties
| Protein name | Sulfate transporter |
|---|
| UniProt accession | P50443 |
|---|
| Gene | SLC26A2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 739 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (302)
Diseases linked to this target (Open Targets).
- multiple epiphyseal dysplasia type 4 · score 0.82
- atelosteogenesis type II · score 0.81
- diastrophic dysplasia · score 0.80
- Achondrogenesis type 1B · score 0.80
- achondrogenesis type IB · score 0.76
- Diastrophic dwarfism · score 0.61
- multiple epiphyseal dysplasia · score 0.56
- sulfate transporter-related osteochondrodysplasia · score 0.54
- osteochondrodysplasia · score 0.54
- Joubert syndrome and related disorders · score 0.50
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P50443-F1 | alphafold | PREDICTED | 80.86 | — |
Amino-acid sequence (739 residues)
MSSESKEQHN VSPRDSAEGN DSYPSGIHLE LQRESSTDFK QFETNDQCRP YHRILIERQE KSDTNFKEFV IKKLQKNCQC SPAKAKNMIL GFLPVLQWLP KYDLKKNILG DVMSGLIVGI LLVPQSIAYS LLAGQEPVYG LYTSFFASII YFLLGTSRHI SVGIFGVLCL MIGETVDREL QKAGYDNAHS APSLGMVSNG STLLNHTSDR ICDKSCYAIM VGSTVTFIAG VYQVAMGFFQ VGFVSVYLSD ALLSGFVTGA SFTILTSQAK YLLGLNLPRT NGVGSLITTW IHVFRNIHKT NLCDLITSLL CLLVLLPTKE LNEHFKSKLK APIPIELVVV VAATLASHFG KLHENYNSSI AGHIPTGFMP PKVPEWNLIP SVAVDAIAIS IIGFAITVSL SEMFAKKHGY TVKANQEMYA IGFCNIIPSF FHCFTTSAAL AKTLVKESTG CHTQLSGVVT ALVLLLVLLV IAPLFYSLQK SVLGVITIVN LRGALRKFRD LPKMWSISRM DTVIWFVTML SSALLSTEIG LLVGVCFSIF CVILRTQKPK SSLLGLVEES EVFESVSAYK NLQIKPGIKI FRFVAPLYYI NKECFKSALY KQTVNPILIK VAWKKAAKRK IKEKVVTLGG IQDEMSVQLS HDPLELHTIV IDCSAIQFLD TAGIHTLKEV RRDYEAIGIQ VLLAQCNPTV RDSLTNGEYC KKEEENLLFY SVYEAMAFAE VSKNQKGVCV PNGLSLSSD
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