Serpin B9 (SERPINB9)

About Serpin B9

Serpin B9 (SERPINB9) is a protein from Homo sapiens identified by UniProt accession P50453, 376 residues long. MolForge cross-references it against 0 known binders and 143 disease associations.

Target properties

Protein name	Serpin B9
UniProt accession	P50453
Gene	SERPINB9
Organism	Homo sapiens
Length	376 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (143)

Diseases linked to this target (Open Targets).

monocyte count · score 0.38
mean corpuscular volume · score 0.33
neurodegenerative disease · score 0.32
reticulocyte count · score 0.28
mean reticulocyte volume · score 0.28
mean corpuscular hemoglobin concentration · score 0.27
Vitiligo · score 0.26
heart function measurement · score 0.26
HbA1c measurement · score 0.24
platelet component distribution width · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P50453-F1	alphafold	PREDICTED	91.16	—

Amino-acid sequence (376 residues)

METLSNASGT FAIRLLKILC QDNPSHNVFC SPVSISSALA MVLLGAKGNT ATQMAQALSL NTEEDIHRAF QSLLTEVNKA GTQYLLRTAN RLFGEKTCQF LSTFKESCLQ FYHAELKELS FIRAAEESRK HINTWVSKKT EGKIEELLPG SSIDAETRLV LVNAIYFKGK WNEPFDETYT REMPFKINQE EQRPVQMMYQ EATFKLAHVG EVRAQLLELP YARKELSLLV LLPDDGVELS TVEKSLTFEK LTAWTKPDCM KSTEVEVLLP KFKLQEDYDM ESVLRHLGIV DAFQQGKADL SAMSAERDLC LSKFVHKSFV EVNEEGTEAA AASSCFVVAE CCMESGPRFC ADHPFLFFIR HNRANSILFC GRFSSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards