Cysteine and glycine-rich protein 3 (CSRP3)

About Cysteine and glycine-rich protein 3

Cysteine and glycine-rich protein 3 (CSRP3) is a protein from Homo sapiens identified by UniProt accession P50461, 194 residues long. MolForge cross-references it against 0 known binders and 240 disease associations.

Target properties

Protein name	Cysteine and glycine-rich protein 3
UniProt accession	P50461
Gene	CSRP3
Organism	Homo sapiens
Length	194 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (240)

Diseases linked to this target (Open Targets).

hypertrophic cardiomyopathy 12 · score 0.75
dilated cardiomyopathy 1M · score 0.72
hypertrophic cardiomyopathy · score 0.61
Rare familial disorder with hypertrophic cardiomyopathy · score 0.55
mean corpuscular volume · score 0.50
dilated cardiomyopathy · score 0.50
Abnormality of the cardiovascular system · score 0.50
erythrocyte count · score 0.48
mean corpuscular hemoglobin · score 0.46
mean corpuscular hemoglobin concentration · score 0.45

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P50461-F1	alphafold	PREDICTED	73.46	—

Amino-acid sequence (194 residues)

MPNWGGGAKC GACEKTVYHA EEIQCNGRSF HKTCFHCMAC RKALDSTTVA AHESEIYCKV CYGRRYGPKG IGYGQGAGCL STDTGEHLGL QFQQSPKPAR SVTTSNPSKF TAKFGESEKC PRCGKSVYAA EKVMGGGKPW HKTCFRCAIC GKSLESTNVT DKDGELYCKV CYAKNFGPTG IGFGGLTQQV EKKE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards