About Max-interacting protein 1
Max-interacting protein 1 (MXI1) is a protein
from Homo sapiens identified by UniProt accession
P50539, 228 residues long.
MolForge cross-references it against 0 known binders and
125 disease associations.
Target properties
| Protein name | Max-interacting protein 1 |
|---|
| UniProt accession | P50539 |
|---|
| Gene | MXI1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (125)
Diseases linked to this target (Open Targets).
- prostate carcinoma · score 0.55
- Familial prostate cancer · score 0.55
- neurodegenerative disease · score 0.54
- prostate cancer · score 0.45
- platelet count · score 0.45
- neutrophil count · score 0.45
- leukocyte count · score 0.44
- creatinine measurement · score 0.40
- myeloid white cell count · score 0.40
- prostate adenocarcinoma · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P50539-F1 | alphafold | PREDICTED | 72.35 | — |
Amino-acid sequence (228 residues)
MERVKMINVQ RLLEAAEFLE RRERECEHGY ASSFPSMPSP RLQHSKPPRR LSRAQKHSSG SSNTSTANRS THNELEKNRR AHLRLCLERL KVLIPLGPDC TRHTTLGLLN KAKAHIKKLE EAERKSQHQL ENLEREQRFL KWRLEQLQGP QEMERIRMDS IGSTISSDRS DSEREEIEVD VESTEFSHGE VDNISTTSIS DIDDHSSLPS IGSDEGYSSA SVKLSFTS
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