About ETS translocation variant 1
ETS translocation variant 1 (ETV1) is a protein
from Homo sapiens identified by UniProt accession
P50549, 477 residues long.
MolForge cross-references it against 0 known binders and
402 disease associations.
Target properties
| Protein name | ETS translocation variant 1 |
|---|
| UniProt accession | P50549 |
|---|
| Gene | ETV1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 477 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (402)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.46
- lymphocyte count · score 0.46
- platelet count · score 0.45
- body height · score 0.43
- hair color · score 0.42
- self reported educational attainment · score 0.40
- myeloid white cell count · score 0.38
- mathematical ability · score 0.38
- leukocyte count · score 0.38
- esophageal adenocarcinoma · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P50549-F1 | alphafold | PREDICTED | 58.47 | — |
Amino-acid sequence (477 residues)
MDGFYDQQVP YMVTNSQRGR NCNEKPTNVR KRKFINRDLA HDSEELFQDL SQLQETWLAE AQVPDNDEQF VPDYQAESLA FHGLPLKIKK EPHSPCSEIS SACSQEQPFK FSYGEKCLYN VSAYDQKPQV GMRPSNPPTP SSTPVSPLHH ASPNSTHTPK PDRAFPAHLP PSQSIPDSSY PMDHRFRRQL SEPCNSFPPL PTMPREGRPM YQRQMSEPNI PFPPQGFKQE YHDPVYEHNT MVGSAASQSF PPPLMIKQEP RDFAYDSEVP SCHSIYMRQE GFLAHPSRTE GCMFEKGPRQ FYDDTCVVPE KFDGDIKQEP GMYREGPTYQ RRGSLQLWQF LVALLDDPSN SHFIAWTGRG MEFKLIEPEE VARRWGIQKN RPAMNYDKLS RSLRYYYEKG IMQKVAGERY VYKFVCDPEA LFSMAFPDNQ RPLLKTDMER HINEEDTVPL SHFDESMAYM PEGGCCNPHP YNEGYVY
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