Ras association domain-containing protein 2 (RASSF2)

About Ras association domain-containing protein 2

Ras association domain-containing protein 2 (RASSF2) is a protein from Homo sapiens identified by UniProt accession P50749, 326 residues long. MolForge cross-references it against 0 known binders and 165 disease associations.

Target properties

Protein name	Ras association domain-containing protein 2
UniProt accession	P50749
Gene	RASSF2
Organism	Homo sapiens
Length	326 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P50749-F1	alphafold	PREDICTED	77.87	—

Amino-acid sequence (326 residues)

MDYSHQTSLV PCGQDKYISK NELLLHLKTY NLYYEGQNLQ LRHREEEDEF IVEGLLNISW GLRRPIRLQM QDDNERIRPP PSSSSWHSGC NLGAQGTTLK PLTVPKVQIS EVDAPPEGDQ MPSSTDSRGL KPLQEDTPQL MRTRSDVGVR RRGNVRTPSD QRRIRRHRFS INGHFYNHKT SVFTPAYGSV TNVRINSTMT TPQVLKLLLN KFKIENSAEE FALYVVHTSG EKQKLKATDY PLIARILQGP CEQISKVFLM EKDQVEEVTY DVAQYIKFEM PVLKSFIQKL QEEEDREVKK LMRKYTVLRL MIRQRLEEIA ETPATI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards