About Basal cell adhesion molecule
Basal cell adhesion molecule (BCAM) is a protein
from Homo sapiens identified by UniProt accession
P50895, 628 residues long.
MolForge cross-references it against 0 known binders and
152 disease associations.
Target properties
| Protein name | Basal cell adhesion molecule |
|---|
| UniProt accession | P50895 |
|---|
| Gene | BCAM |
|---|
| Organism | Homo sapiens |
|---|
| Length | 628 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (152)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.33
- low density lipoprotein cholesterol measurement · score 0.31
- apolipoprotein B measurement · score 0.28
- response to statin · score 0.28
- metabolic syndrome · score 0.27
- neoplasm · score 0.08
- triglyceride measurement · score 0.08
- total cholesterol measurement · score 0.08
- breast cancer · score 0.07
- urinary bladder carcinoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P50895-F1 | alphafold | PREDICTED | 83.53 | — |
Amino-acid sequence (628 residues)
MEPPDAPAQA RGAPRLLLLA VLLAAHPDAQ AEVRLSVPPL VEVMRGKSVI LDCTPTGTHD HYMLEWFLTD RSGARPRLAS AEMQGSELQV TMHDTRGRSP PYQLDSQGRL VLAEAQVGDE RDYVCVVRAG AAGTAEATAR LNVFAKPEAT EVSPNKGTLS VMEDSAQEIA TCNSRNGNPA PKITWYRNGQ RLEVPVEMNP EGYMTSRTVR EASGLLSLTS TLYLRLRKDD RDASFHCAAH YSLPEGRHGR LDSPTFHLTL HYPTEHVQFW VGSPSTPAGW VREGDTVQLL CRGDGSPSPE YTLFRLQDEQ EEVLNVNLEG NLTLEGVTRG QSGTYGCRVE DYDAADDVQL SKTLELRVAY LDPLELSEGK VLSLPLNSSA VVNCSVHGLP TPALRWTKDS TPLGDGPMLS LSSITFDSNG TYVCEASLPT VPVLSRTQNF TLLVQGSPEL KTAEIEPKAD GSWREGDEVT LICSARGHPD PKLSWSQLGG SPAEPIPGRQ GWVSSSLTLK VTSALSRDGI SCEASNPHGN KRHVFHFGTV SPQTSQAGVA VMAVAVSVGL LLLVVAVFYC VRRKGGPCCR QRREKGAPPP GEPGLSHSGS EQPEQTGLLM GGASGGARGG SGGFGDEC
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