Ras-related protein Rab-5C (RAB5C)

About Ras-related protein Rab-5C

Ras-related protein Rab-5C (RAB5C) is a protein from Homo sapiens identified by UniProt accession P51148, 216 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.

Target properties

Protein name	Ras-related protein Rab-5C
UniProt accession	P51148
Gene	RAB5C
Organism	Homo sapiens
Length	216 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51148-F1	alphafold	PREDICTED	84.22	—

Amino-acid sequence (216 residues)

MAGRGGAARP NGPAAGNKIC QFKLVLLGES AVGKSSLVLR FVKGQFHEYQ ESTIGAAFLT QTVCLDDTTV KFEIWDTAGQ ERYHSLAPMY YRGAQAAIVV YDITNTDTFA RAKNWVKELQ RQASPNIVIA LAGNKADLAS KRAVEFQEAQ AYADDNSLLF METSAKTAMN VNEIFMAIAK KLPKNEPQNA TGAPGRNRGV DLQENNPASR SQCCSN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards