Ras-related protein Rab-7a (RAB7A)

About Ras-related protein Rab-7a

Ras-related protein Rab-7a (RAB7A) is a protein from Homo sapiens identified by UniProt accession P51149, 207 residues long. MolForge cross-references it against 0 known binders and 157 disease associations.

Target properties

Protein name	Ras-related protein Rab-7a
UniProt accession	P51149
Gene	RAB7A
Organism	Homo sapiens
Length	207 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51149-F1	alphafold	PREDICTED	88.69	—

Amino-acid sequence (207 residues)

MTSRKKVLLK VIILGDSGVG KTSLMNQYVN KKFSNQYKAT IGADFLTKEV MVDDRLVTMQ IWDTAGQERF QSLGVAFYRG ADCCVLVFDV TAPNTFKTLD SWRDEFLIQA SPRDPENFPF VVLGNKIDLE NRQVATKRAQ AWCYSKNNIP YFETSAKEAI NVEQAFQTIA RNALKQETEV ELYNEFPEPI KLDKNDRAKA SAESCSC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards