Ras-related protein Rab-27A (RAB27A)

About Ras-related protein Rab-27A

Ras-related protein Rab-27A (RAB27A) is a protein from Homo sapiens identified by UniProt accession P51159, 221 residues long. MolForge cross-references it against 0 known binders and 369 disease associations.

Target properties

Protein name	Ras-related protein Rab-27A
UniProt accession	P51159
Gene	RAB27A
Organism	Homo sapiens
Length	221 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51159-F1	alphafold	PREDICTED	83.95	—

Amino-acid sequence (221 residues)

MSDGDYDYLI KFLALGDSGV GKTSVLYQYT DGKFNSKFIT TVGIDFREKR VVYRASGPDG ATGRGQRIHL QLWDTAGQER FRSLTTAFFR DAMGFLLLFD LTNEQSFLNV RNWISQLQMH AYCENPDIVL CGNKSDLEDQ RVVKEEEAIA LAEKYGIPYF ETSAANGTNI SQAIEMLLDL IMKRMERCVD KSWIPEGVVR SNGHASTDQL SEEKEKGACG C

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards