Death-associated protein 1 (DAP)

About Death-associated protein 1

Death-associated protein 1 (DAP) is a protein from Homo sapiens identified by UniProt accession P51397, 102 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.

Target properties

Protein name	Death-associated protein 1
UniProt accession	P51397
Gene	DAP
Organism	Homo sapiens
Length	102 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (61)

Diseases linked to this target (Open Targets).

body height · score 0.39
ulcerative colitis · score 0.34
eosinophil count · score 0.32
Crohn's disease · score 0.31
inflammatory bowel disease · score 0.31
basophil count · score 0.30
lymphocyte percentage of leukocytes · score 0.29
erythrocyte count · score 0.27
rheumatoid arthritis · score 0.25
neurodegenerative disease · score 0.24

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51397-F1	alphafold	PREDICTED	69.18	—

Amino-acid sequence (102 residues)

MSSPPEGKLE TKAGHPPAVK AGGMRIVQKH PHTGDTKEEK DKDDQEWESP SPPKPTVFIS GVIARGDKDF PPAAAQVAHQ KPHASMDKHP SPRTQHIQQP RK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards