Small ribosomal subunit protein mS29 (DAP3)

About Small ribosomal subunit protein mS29

Small ribosomal subunit protein mS29 (DAP3) is a protein from Homo sapiens identified by UniProt accession P51398, 398 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.

Target properties

Protein name	Small ribosomal subunit protein mS29
UniProt accession	P51398
Gene	DAP3
Organism	Homo sapiens
Length	398 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (64)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.49
grange syndrome · score 0.30
genetic disorder · score 0.19
cancer · score 0.10
neoplasm · score 0.09
isolated asymptomatic elevation of creatine phosphokinase · score 0.07
body mass index · score 0.05
pentosuria · score 0.05
neutrophil count · score 0.04
blood urea nitrogen measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51398-F1	alphafold	PREDICTED	85.03	—

Amino-acid sequence (398 residues)

MMLKGITRLI SRIHKLDPGR FLHMGTQARQ SIAAHLDNQV PVESPRAISR TNENDPAKHG DQHEGQHYNI SPQDLETVFP HGLPPRFVMQ VKTFSEACLM VRKPALELLH YLKNTSFAYP AIRYLLYGEK GTGKTLSLCH VIHFCAKQDW LILHIPDAHL WVKNCRDLLQ SSYNKQRFDQ PLEASTWLKN FKTTNERFLN QIKVQEKYVW NKRESTEKGS PLGEVVEQGI TRVRNATDAV GIVLKELKRQ SSLGMFHLLV AVDGINALWG RTTLKREDKS PIAPEELALV HNLRKMMKND WHGGAIVSAL SQTGSLFKPR KAYLPQELLG KEGFDALDPF IPILVSNYNP KEFESCIQYY LENNWLQHEK APTEEGKKEL LFLSNANPSL LERHCAYL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards