About Zinc finger protein 80
Zinc finger protein 80 (ZNF80) is a protein
from Homo sapiens identified by UniProt accession
P51504, 273 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Zinc finger protein 80 |
| UniProt accession | P51504 |
| Gene | ZNF80 |
| Organism | Homo sapiens |
| Length | 273 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- emotional symptom measurement · score 0.08
- feeling emotionally hurt measurement · score 0.08
- hair shape measurement · score 0.05
- body mass index · score 0.05
- balding measurement · score 0.05
- smoking initiation · score 0.04
- smoking status measurement · score 0.04
- PHF-tau measurement · score 0.04
- body height · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P51504-F1 | alphafold | PREDICTED | 80.21 | — |
Amino-acid sequence (273 residues)
MSPKRDGLGT GDGLHSQVLQ EQVSTGDNLH ECDSQGPSKD TLVREGKTYK CKECGSVFNK NSLLVRHQQI HTGVKPYECQ ECGKAFPEKV DFVRPMRIHT GEKPCKCVEC GKVFNRRSHL LCYRQIHTGE KPYECSECGK TFSYHSVFIQ HRVTHTGEKL FGCKECGKTF YYNSSLTRHM KIHTGEKPCK CSECGKTFTY RSVFFRHSMT HTAGKPYECK ECGKGFYYSY SLTRHTRSHT GEKPYECLEH RKDFGYHSAF AQQSKIHSGG KNL
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