Zinc finger protein 80 (ZNF80)

Homo sapiens — UniProt P51504

Gene: ZNF80Homo sapiensSwissProt reviewed

About Zinc finger protein 80

Zinc finger protein 80 (ZNF80) is a protein from Homo sapiens identified by UniProt accession P51504, 273 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein nameZinc finger protein 80
UniProt accessionP51504
GeneZNF80
OrganismHomo sapiens
Length273 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (33)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.31
  • emotional symptom measurement · score 0.08
  • feeling emotionally hurt measurement · score 0.08
  • hair shape measurement · score 0.05
  • body mass index · score 0.05
  • balding measurement · score 0.05
  • smoking initiation · score 0.04
  • smoking status measurement · score 0.04
  • PHF-tau measurement · score 0.04
  • body height · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P51504-F1alphafoldPREDICTED80.21—

Amino-acid sequence (273 residues)

MSPKRDGLGT GDGLHSQVLQ EQVSTGDNLH ECDSQGPSKD TLVREGKTYK CKECGSVFNK NSLLVRHQQI HTGVKPYECQ ECGKAFPEKV DFVRPMRIHT GEKPCKCVEC GKVFNRRSHL LCYRQIHTGE KPYECSECGK TFSYHSVFIQ HRVTHTGEKL FGCKECGKTF YYNSSLTRHM KIHTGEKPCK CSECGKTFTY RSVFFRHSMT HTAGKPYECK ECGKGFYYSY SLTRHTRSHT GEKPYECLEH RKDFGYHSAF AQQSKIHSGG KNL

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Quick facts

UniProtP51504
GeneZNF80
OrganismHomo sapiens
Length273
Binders0
Diseases33
View on UniProt