About Zinc finger protein 81
Zinc finger protein 81 (ZNF81) is a protein
from Homo sapiens identified by UniProt accession
P51508, 661 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Zinc finger protein 81 |
|---|
| UniProt accession | P51508 |
|---|
| Gene | ZNF81 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 661 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- X-linked non-syndromic intellectual disability · score 0.40
- non-syndromic X-linked intellectual disability · score 0.17
- autism · score 0.11
- Intellectual disability · score 0.01
- X-linked intellectual disability · score 0.00
- cancer · score 0.00
- Neurodevelopmental delay · score 0.00
- synovial sarcoma · score 0.00
- metastatic melanoma · score 0.00
- Global developmental delay · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P51508-F1 | alphafold | PREDICTED | 63.08 | — |
Amino-acid sequence (661 residues)
MPANEDAPQP GEHGSACEVS VSFEDVTVDF SREEWQQLDS TQRRLYQDVM LENYSHLLSV GFEVPKPEVI FKLEQGEGPW TLEGEAPHQS CSDGKFGIKP SQRRISGKST FHSEMEGEDT RDDSLYSILE ELWQDAEQIK RCQEKHNKLL SRTTFLNKKI LNTEWDYEYK DFGKFVHPSP NLILSQKRPH KRDSFGKSFK HNLDLHIHNK SNAAKNLDKT IGHGQVFTQN SSYSHHENTH TGVKFCERNQ CGKVLSLKHS LSQNVKFPIG EKANTCTEFG KIFTQRSHFF APQKIHTVEK PHELSKCVNV FTQKPLLSIY LRVHRDEKLY ICTKCGKAFI QNSELIMHEK THTREKPYKC NECGKSFFQV SSLLRHQTTH TGEKLFECSE CGKGFSLNSA LNIHQKIHTG ERHHKCSECG KAFTQKSTLR MHQRIHTGER SYICTQCGQA FIQKAHLIAH QRIHTGEKPY ECSDCGKSFP SKSQLQMHKR IHTGEKPYIC TECGKAFTNR SNLNTHQKSH TGEKSYICAE CGKAFTDRSN FNKHQTIHTG EKPYVCADCG RAFIQKSELI THQRIHTTEK PYKCPDCEKS FSKKPHLKVH QRIHTGEKPY ICAECGKAFT DRSNFNKHQT IHTGDKPYKC SDCGKGFTQK SVLSMHRNIH T
Explore Zinc finger protein 81 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets