Zinc finger protein 83 (ZNF83)

About Zinc finger protein 83

Zinc finger protein 83 (ZNF83) is a protein from Homo sapiens identified by UniProt accession P51522, 516 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Zinc finger protein 83
UniProt accession	P51522
Gene	ZNF83
Organism	Homo sapiens
Length	516 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

hair colour measurement · score 0.24
Red cell distribution width · score 0.17
ulcerative colitis · score 0.07
neoplasm · score 0.07
cancer · score 0.02
urinary bladder carcinoma · score 0.02
psoriasis · score 0.01
ovarian carcinoma · score 0.01
hepatocellular carcinoma · score 0.01
squamous cell carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51522-F1	alphafold	PREDICTED	75.51	—

Amino-acid sequence (516 residues)

MHGRKDDAQK QPVKNQLGLN PQSHLPELQL FQAEGKIYKY DHMEKSVNSS SLVSPPQRIS STVKTHISHT YECNFVDSLF TQKEKANIGT EHYKCSERGK AFHQGLHFTI HQIIHTKETQ FKCDICGKIF NKKSNLASHQ RIHTGEKPYK CNECGKVFHN MSHLAQHRRI HTGEKPYKCN ECGKVFNQIS HLAQHQRIHT GEKPYKCNEC GKVFHQISHL AQHRTIHTGE KPYECNKCGK VFSRNSYLVQ HLIIHTGEKP YRCNVCGKVF HHISHLAQHQ RIHTGEKPYK CNECGKVFSH KSSLVNHWRI HTGEKPYKCN ECGKVFSHKS SLVNHWRIHT GEKPYKCNEC GKVFSRNSYL AQHLIIHAGE KPYKCDECDK AFSQNSHLVQ HHRIHTGEKP YKCDECGKVF SQNSYLAYHW RIHTGEKAYK CNECGKVFGL NSSLAHHRKI HTGEKPFKCN ECGKAFSMRS SLTNHHAIHT GEKHFKCNEC GKLFRDNSYL VRHQRFHAGK KSNTCN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards