About Zinc finger protein 84
Zinc finger protein 84 (ZNF84) is a protein
from Homo sapiens identified by UniProt accession
P51523, 738 residues long.
MolForge cross-references it against 0 known binders and
31 disease associations.
Target properties
| Protein name | Zinc finger protein 84 |
|---|
| UniProt accession | P51523 |
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| Gene | ZNF84 |
|---|
| Organism | Homo sapiens |
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| Length | 738 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (31)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- lysosomal storage disease · score 0.24
- multiple sclerosis · score 0.24
- Alzheimer disease · score 0.24
- Parkinson disease · score 0.24
- mean platelet volume · score 0.09
- cardiovascular disease · score 0.08
- BMI-adjusted waist-hip ratio · score 0.08
- mean corpuscular hemoglobin concentration · score 0.07
- cortical thickness · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P51523-F1 | alphafold | PREDICTED | 75.70 | — |
Amino-acid sequence (738 residues)
MTMLQESFSF DDLSVDFTQK EWQLLDPSQK NLYKDVMLEN YSSLVSLGYE VMKPDVIFKL EQGEEPWVGD GEIPSSDSPE VWKVDGNMMW HQDNQDKLKI IKRGHECDAF GKNFNLNMNF VPLRKSNSEG DLDGLILKHH LDLLIPKGDY GKAESDDFNV FDNFFLHSKP EDTDTWLKYY DCDKYKESYK KSQIIIYHRN RLGEKLYECS ECRKRFSKKP SLIKHQSRHI RDIAFGCGNC GKTFPQKSQF ITHHRTHTGE KPYNCSQCGK AFSQKSQLTS HQRTHTGEKP YECGECGKAF SRKSHLISHW RTHTGEKPYG CNECGRAFSE KSNLINHQRI HTGEKPFECR ECGKAFSRKS QLVTHHRTHT GTKPFGCSDC RKAFFEKSEL IRHQTIHTGE KPYECSECRK AFRERSSLIN HQRTHTGEKP HGCIQCGKAF SQKSHLISHQ MTHTGEKPFI CSKCGKAFSR KSQLVRHQRT HTGEKPYECS ECGKAFSEKL SLTNHQRIHT GEKPYVCSEC GKAFCQKSHL ISHQRTHTGE KPYECSECGK AFGEKSSLAT HQRTHTGEKP YECRDCEKAF SQKSQLNTHQ RIHTGEKPYE CSLCRKAFFE KSELIRHLRT HTGEKPYECN ECRKAFREKS SLINHQRIHT GEKPFECSEC GKAFSRKSHL IPHQRTHTGE KPYGCSECRK AFSQKSQLVN HQRIHTGEKP YRCIECGKAF SQKSQLINHQ RTHTVKKS
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