About B-cell receptor-associated protein 31
B-cell receptor-associated protein 31 (BCAP31) is a protein
from Homo sapiens identified by UniProt accession
P51572, 246 residues long.
MolForge cross-references it against 0 known binders and
96 disease associations.
Target properties
| Protein name | B-cell receptor-associated protein 31 |
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| UniProt accession | P51572 |
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| Gene | BCAP31 |
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| Organism | Homo sapiens |
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| Length | 246 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (96)
Diseases linked to this target (Open Targets).
- severe motor and intellectual disabilities-sensorineural deafness-dystonia syndrome · score 0.75
- CADDS · score 0.51
- genetic disorder · score 0.44
- neurodegenerative disease · score 0.43
- breast adenocarcinoma · score 0.25
- endometrial cancer · score 0.23
- Global developmental delay · score 0.12
- Seizure · score 0.12
- Microcephaly · score 0.11
- hepatocellular carcinoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P51572-F1 | alphafold | PREDICTED | 84.39 | — |
Amino-acid sequence (246 residues)
MSLQWTAVAT FLYAEVFVVL LLCIPFISPK RWQKIFKSRL VELLVSYGNT FFVVLIVILV LLVIDAVREI RKYDDVTEKV NLQNNPGAME HFHMKLFRAQ RNLYIAGFSL LLSFLLRRLV TLISQQATLL ASNEAFKKQA ESASEAAKKY MEENDQLKKG AAVDGGKLDV GNAEVKLEEE NRSLKADLQK LKDELASTKQ KLEKAENQVL AMRKQSEGLT KEYDRLLEEH AKLQAAVDGP MDKKEE
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