About Cytochrome P450 2J2
Cytochrome P450 2J2 (CYP2J2) is a protein
from Homo sapiens identified by UniProt accession
P51589, 502 residues long.
MolForge cross-references it against 0 known binders and
153 disease associations.
Target properties
| Protein name | Cytochrome P450 2J2 |
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| UniProt accession | P51589 |
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| Gene | CYP2J2 |
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| Organism | Homo sapiens |
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| Length | 502 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (153)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.27
- attention deficit hyperactivity disorder · score 0.26
- antisocial behaviour measurement · score 0.26
- substance abuse · score 0.26
- cutaneous melanoma · score 0.23
- endometrial cancer · score 0.16
- smoking status measurement · score 0.15
- head and neck squamous cell carcinoma · score 0.14
- cardiac hypertrophy · score 0.08
- coronary artery disease · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P51589-F1 | alphafold | PREDICTED | 93.70 | — |
Amino-acid sequence (502 residues)
MLAAMGSLAA ALWAVVHPRT LLLGTVAFLL AADFLKRRRP KNYPPGPWRL PFLGNFFLVD FEQSHLEVQL FVKKYGNLFS LELGDISAVL ITGLPLIKEA LIHMDQNFGN RPVTPMREHI FKKNGLIMSS GQAWKEQRRF TLTALRNFGL GKKSLEERIQ EEAQHLTEAI KEENGQPFDP HFKINNAVSN IICSITFGER FEYQDSWFQQ LLKLLDEVTY LEASKTCQLY NVFPWIMKFL PGPHQTLFSN WKKLKLFVSH MIDKHRKDWN PAETRDFIDA YLKEMSKHTG NPTSSFHEEN LICSTLDLFF AGTETTSTTL RWALLYMALY PEIQEKVQAE IDRVIGQGQQ PSTAARESMP YTNAVIHEVQ RMGNIIPLNV PREVTVDTTL AGYHLPKGTM ILTNLTALHR DPTEWATPDT FNPDHFLENG QFKKREAFMP FSIGKRACLG EQLARTELFI FFTSLMQKFT FRPPNNEKLS LKFRMGITIS PVSHRLCAVP QV
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