About Caveolin-2
Caveolin-2 (CAV2) is a protein
from Homo sapiens identified by UniProt accession
P51636, 162 residues long.
MolForge cross-references it against 0 known binders and
244 disease associations.
Target properties
| Protein name | Caveolin-2 |
| UniProt accession | P51636 |
| Gene | CAV2 |
| Organism | Homo sapiens |
| Length | 162 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (244)
Diseases linked to this target (Open Targets).
- body height · score 0.39
- medical procedure · score 0.32
- intraocular pressure measurement · score 0.26
- neutrophil percentage of leukocytes · score 0.24
- open-angle glaucoma · score 0.24
- glaucoma · score 0.23
- lymphocyte percentage of leukocytes · score 0.23
- atrial fibrillation · score 0.21
- heart rate response to exercise · score 0.20
- systolic blood pressure · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-P51636-F1 | alphafold | PREDICTED | 78.39 | — |
Amino-acid sequence (162 residues)
MGLETEKADV QLFMDDDSYS HHSGLEYADP EKFADSDQDR DPHRLNSHLK LGFEDVIAEP VTTHSFDKVW ICSHALFEIS KYVMYKFLTV FLAIPLAFIA GILFATLSCL HIWILMPFVK TCLMVLPSVQ TIWKSVTDVI IAPLCTSVGR CFSSVSLQLS QD
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