Caveolin-2 (CAV2)

Homo sapiens — UniProt P51636

Gene: CAV2Homo sapiensSwissProt reviewed

About Caveolin-2

Caveolin-2 (CAV2) is a protein from Homo sapiens identified by UniProt accession P51636, 162 residues long. MolForge cross-references it against 0 known binders and 244 disease associations.

Target properties

Protein nameCaveolin-2
UniProt accessionP51636
GeneCAV2
OrganismHomo sapiens
Length162 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (244)

Diseases linked to this target (Open Targets).

  • body height · score 0.39
  • medical procedure · score 0.32
  • intraocular pressure measurement · score 0.26
  • neutrophil percentage of leukocytes · score 0.24
  • open-angle glaucoma · score 0.24
  • glaucoma · score 0.23
  • lymphocyte percentage of leukocytes · score 0.23
  • atrial fibrillation · score 0.21
  • heart rate response to exercise · score 0.20
  • systolic blood pressure · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P51636-F1alphafoldPREDICTED78.39—

Amino-acid sequence (162 residues)

MGLETEKADV QLFMDDDSYS HHSGLEYADP EKFADSDQDR DPHRLNSHLK LGFEDVIAEP VTTHSFDKVW ICSHALFEIS KYVMYKFLTV FLAIPLAFIA GILFATLSCL HIWILMPFVK TCLMVLPSVQ TIWKSVTDVI IAPLCTSVGR CFSSVSLQLS QD

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Quick facts

UniProtP51636
GeneCAV2
OrganismHomo sapiens
Length162
Binders0
Diseases244
View on UniProt