26S proteasome non-ATPase regulatory subunit 7 (PSMD7)

About 26S proteasome non-ATPase regulatory subunit 7

26S proteasome non-ATPase regulatory subunit 7 (PSMD7) is a protein from Homo sapiens identified by UniProt accession P51665, 324 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.

Target properties

Protein name	26S proteasome non-ATPase regulatory subunit 7
UniProt accession	P51665
Gene	PSMD7
Organism	Homo sapiens
Length	324 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (55)

Diseases linked to this target (Open Targets).

HIV infection · score 0.46
neurodegenerative disease · score 0.32
lung adenocarcinoma · score 0.30
breast adenocarcinoma · score 0.30
endometrial cancer · score 0.29
squamous cell lung carcinoma · score 0.28
clear cell renal carcinoma · score 0.27
gastric adenocarcinoma · score 0.27
diet measurement · score 0.22
systolic blood pressure · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51665-F1	alphafold	PREDICTED	83.11	—

Amino-acid sequence (324 residues)

MPELAVQKVV VHPLVLLSVV DHFNRIGKVG NQKRVVGVLL GSWQKKVLDV SNSFAVPFDE DDKDDSVWFL DHDYLENMYG MFKKVNARER IVGWYHTGPK LHKNDIAINE LMKRYCPNSV LVIIDVKPKD LGLPTEAYIS VEEVHDDGTP TSKTFEHVTS EIGAEEAEEV GVEHLLRDIK DTTVGTLSQR ITNQVHGLKG LNSKLLDIRS YLEKVATGKL PINHQIIYQL QDVFNLLPDV SLQEFVKAFY LKTNDQMVVV YLASLIRSVV ALHNLINNKI ANRDAEKKEG QEKEESKKDR KEDKEKDKDK EKSDVKKEEK KEKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards