Ubiquitin-conjugating enzyme E2 D1 (UBE2D1)

About Ubiquitin-conjugating enzyme E2 D1

Ubiquitin-conjugating enzyme E2 D1 (UBE2D1) is a protein from Homo sapiens identified by UniProt accession P51668, 147 residues long. MolForge cross-references it against 0 known binders and 120 disease associations.

Target properties

Protein name	Ubiquitin-conjugating enzyme E2 D1
UniProt accession	P51668
Gene	UBE2D1
Organism	Homo sapiens
Length	147 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (120)

Diseases linked to this target (Open Targets).

mitochondrial DNA measurement · score 0.29
clear cell renal carcinoma · score 0.26
ulcerative colitis · score 0.24
monocyte count · score 0.20
gut microbiome measurement · score 0.19
squamous cell lung carcinoma · score 0.19
lung adenocarcinoma · score 0.09
hepatocellular carcinoma · score 0.08
gluthathione peroxidase deficiency · score 0.06
Rh deficiency syndrome · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51668-F1	alphafold	PREDICTED	96.37	—

Amino-acid sequence (147 residues)

MALKRIQKEL SDLQRDPPAH CSAGPVGDDL FHWQATIMGP PDSAYQGGVF FLTVHFPTDY PFKPPKIAFT TKIYHPNINS NGSICLDILR SQWSPALTVS KVLLSICSLL CDPNPDDPLV PDIAQIYKSD KEKYNRHARE WTQKYAM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards