C-C chemokine receptor type 9 (CCR9)

About C-C chemokine receptor type 9

C-C chemokine receptor type 9 (CCR9) is a protein from Homo sapiens identified by UniProt accession P51686, 369 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.

Target properties

Protein name	C-C chemokine receptor type 9
UniProt accession	P51686
Gene	CCR9
Organism	Homo sapiens
Length	369 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (81)

Diseases linked to this target (Open Targets).

Crohn's disease · score 0.36
ovarian cancer · score 0.26
CCL4 measurement · score 0.26
blood protein measurement · score 0.16
aspartate aminotransferase measurement · score 0.15
Bardet-Biedl syndrome · score 0.12
eosinophil percentage of leukocytes · score 0.12
eosinophil count · score 0.11
Hirschsprung disease · score 0.11
MODY · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51686-F1	alphafold	PREDICTED	83.46	—

Amino-acid sequence (369 residues)

MTPTDFTSPI PNMADDYGSE STSSMEDYVN FNFTDFYCEK NNVRQFASHF LPPLYWLVFI VGALGNSLVI LVYWYCTRVK TMTDMFLLNL AIADLLFLVT LPFWAIAAAD QWKFQTFMCK VVNSMYKMNF YSCVLLIMCI SVDRYIAIAQ AMRAHTWREK RLLYSKMVCF TIWVLAAALC IPEILYSQIK EESGIAICTM VYPSDESTKL KSAVLTLKVI LGFFLPFVVM ACCYTIIIHT LIQAKKSSKH KALKVTITVL TVFVLSQFPY NCILLVQTID AYAMFISNCA VSTNIDICFQ VTQTIAFFHS CLNPVLYVFV GERFRRDLVK TLKNLGCISQ AQWVSFTRRE GSLKLSSMLL ETTSGALSL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards