Dynein light chain Tctex-type 3 (DYNLT3)

About Dynein light chain Tctex-type 3

Dynein light chain Tctex-type 3 (DYNLT3) is a protein from Homo sapiens identified by UniProt accession P51808, 116 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

Target properties

Protein name	Dynein light chain Tctex-type 3
UniProt accession	P51808
Gene	DYNLT3
Organism	Homo sapiens
Length	116 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (32)

Diseases linked to this target (Open Targets).

neoplasm · score 0.05
cancer · score 0.02
oligodendroglioma · score 0.02
astrocytoma · score 0.01
Ovarian Endometrioid Adenocarcinoma · score 0.01
ovarian serous adenocarcinoma · score 0.01
breast cancer · score 0.01
Parkinson disease · score 0.01
ovarian serous cystadenocarcinoma · score 0.00
melanoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51808-F1	alphafold	PREDICTED	91.15	—

Amino-acid sequence (116 residues)

MEEYHRHCDE VGFNAEEAHN IVKECVDGVL GGEDYNHNNI NQWTASIVEQ SLTHLVKLGK AYKYIVTCAV VQKSAYGFHT ASSCFWDTTS DGTCTVRWEN RTMNCIVNVF AIAIVL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards