Vesicle-associated membrane protein 7 (VAMP7)

About Vesicle-associated membrane protein 7

Vesicle-associated membrane protein 7 (VAMP7) is a protein from Homo sapiens identified by UniProt accession P51809, 220 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Vesicle-associated membrane protein 7
UniProt accession	P51809
Gene	VAMP7
Organism	Homo sapiens
Length	220 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.23
lung adenocarcinoma · score 0.18
alcohol consumption measurement · score 0.09
Alzheimer disease · score 0.01
multiple myeloma · score 0.00
tetanus · score 0.00
macroglobulinemia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51809-F1	alphafold	PREDICTED	84.28	—

Amino-acid sequence (220 residues)

MAILFAVVAR GTTILAKHAW CGGNFLEVTE QILAKIPSEN NKLTYSHGNY LFHYICQDRI VYLCITDDDF ERSRAFNFLN EIKKRFQTTY GSRAQTALPY AMNSEFSSVL AAQLKHHSEN KGLDKVMETQ AQVDELKGIM VRNIDLVAQR GERLELLIDK TENLVDSSVT FKTTSRNLAR AMCMKNLKLT IIIIIVSIVF IYIIVSPLCG GFTWPSCVKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards