About Cytoplasmic tyrosine-protein kinase BMX
Cytoplasmic tyrosine-protein kinase BMX (BMX) is a protein
from Homo sapiens identified by UniProt accession
P51813, 675 residues long.
MolForge cross-references it against 0 known binders and
127 disease associations.
Target properties
| Protein name | Cytoplasmic tyrosine-protein kinase BMX |
|---|
| UniProt accession | P51813 |
|---|
| Gene | BMX |
|---|
| Organism | Homo sapiens |
|---|
| Length | 675 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (15)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (127)
Diseases linked to this target (Open Targets).
- alopecia areata · score 0.50
- Vitiligo · score 0.36
- breast adenocarcinoma · score 0.27
- ovarian cancer · score 0.23
- endometrial cancer · score 0.23
- head and neck squamous cell carcinoma · score 0.20
- esophageal cancer · score 0.15
- gastric adenocarcinoma · score 0.13
- rheumatoid arthritis · score 0.09
- neoplasm · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P51813-F1 | alphafold | PREDICTED | 75.72 | — |
Amino-acid sequence (675 residues)
MDTKSILEEL LLKRSQQKKK MSPNNYKERL FVLTKTNLSY YEYDKMKRGS RKGSIEIKKI RCVEKVNLEE QTPVERQYPF QIVYKDGLLY VYASNEESRS QWLKALQKEI RGNPHLLVKY HSGFFVDGKF LCCQQSCKAA PGCTLWEAYA NLHTAVNEEK HRVPTFPDRV LKIPRAVPVL KMDAPSSSTT LAQYDNESKK NYGSQPPSSS TSLAQYDSNS KKIYGSQPNF NMQYIPREDF PDWWQVRKLK SSSSSEDVAS SNQKERNVNH TTSKISWEFP ESSSSEEEEN LDDYDWFAGN ISRSQSEQLL RQKGKEGAFM VRNSSQVGMY TVSLFSKAVN DKKGTVKHYH VHTNAENKLY LAENYCFDSI PKLIHYHQHN SAGMITRLRH PVSTKANKVP DSVSLGNGIW ELKREEITLL KELGSGQFGV VQLGKWKGQY DVAVKMIKEG SMSEDEFFQE AQTMMKLSHP KLVKFYGVCS KEYPIYIVTE YISNGCLLNY LRSHGKGLEP SQLLEMCYDV CEGMAFLESH QFIHRDLAAR NCLVDRDLCV KVSDFGMTRY VLDDQYVSSV GTKFPVKWSA PEVFHYFKYS SKSDVWAFGI LMWEVFSLGK QPYDLYDNSQ VVLKVSQGHR LYRPHLASDT IYQIMYSCWH ELPEKRPTFQ QLLSSIEPLR EKDKH
Explore Cytoplasmic tyrosine-protein kinase BMX with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets