Protein CRIPTO3 (CRIPTO3)

About Protein CRIPTO3

Protein CRIPTO3 (CRIPTO3) is a protein from Homo sapiens identified by UniProt accession P51864, 188 residues long. MolForge cross-references it against 0 known binders and 164 disease associations.

Target properties

Protein name	Protein CRIPTO3
UniProt accession	P51864
Gene	CRIPTO3
Organism	Homo sapiens
Length	188 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (164)

Diseases linked to this target (Open Targets).

response to statin · score 0.17
familial hypercholesterolemia · score 0.13
neoplasm · score 0.08
total cholesterol measurement · score 0.07
chronic lymphocytic leukemia · score 0.06
Disorder of lipid metabolism · score 0.05
nail-patella syndrome · score 0.03
hematoma · score 0.03
infection · score 0.03
infect · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P51864-F1	alphafold	PREDICTED	66.96	—

Amino-acid sequence (188 residues)

MDCRKMVRFS YSVIWIMAIS KAFELGLVAG LGHQEFARPS RGDLAFRDDS IWPQEEPAIR PRSSQRVLPM GIQHSKELNR TCCLNGGTCM LESFCACPPS FYGRNCEHDV RKENCGSVPH DTWLPKKCSL CKCWHGQLRC FPQAFLPGCD GLVMDEHLVA SRTPELPPSA RTTTFMLAGI CLSIQSYY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards