About Calponin-1
Calponin-1 (CNN1) is a protein
from Homo sapiens identified by UniProt accession
P51911, 297 residues long.
MolForge cross-references it against 0 known binders and
113 disease associations.
Target properties
| Protein name | Calponin-1 |
|---|
| UniProt accession | P51911 |
|---|
| Gene | CNN1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 297 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (113)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- antiphospholipid antibody measurement · score 0.14
- neoplasm · score 0.09
- cancer · score 0.08
- breast cancer · score 0.08
- blood protein measurement · score 0.06
- colorectal cancer · score 0.05
- Barrett's esophagus · score 0.05
- breast carcinoma · score 0.04
- Metaphyseal chondrodysplasia, Schmid type · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P51911-F1 | alphafold | PREDICTED | 71.72 | — |
Amino-acid sequence (297 residues)
MSSAHFNRGP AYGLSAEVKN KLAQKYDHQR EQELREWIEG VTGRRIGNNF MDGLKDGIIL CEFINKLQPG SVKKINESTQ NWHQLENIGN FIKAITKYGV KPHDIFEAND LFENTNHTQV QSTLLALASM AKTKGNKVNV GVKYAEKQER KFEPGKLREG RNIIGLQMGT NKFASQQGMT AYGTRRHLYD PKLGTDQPLD QATISLQMGT NKGASQAGMT APGTKRQIFE PGLGMEHCDT LNVSLQMGSN KGASQRGMTV YGLPRQVYDP KYCLTPEYPE LGEPAHNHHA HNYYNSA
Explore Calponin-1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets