About Cyclin-G1
Cyclin-G1 (CCNG1) is a protein
from Homo sapiens identified by UniProt accession
P51959, 295 residues long.
MolForge cross-references it against 0 known binders and
139 disease associations.
Target properties
| Protein name | Cyclin-G1 |
|---|
| UniProt accession | P51959 |
|---|
| Gene | CCNG1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 295 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (139)
Diseases linked to this target (Open Targets).
- ceramide measurement · score 0.26
- glioblastoma multiforme · score 0.26
- age-related hearing impairment · score 0.26
- head and neck squamous cell carcinoma · score 0.23
- endometrial cancer · score 0.23
- squamous cell lung carcinoma · score 0.23
- lung adenocarcinoma · score 0.23
- aortic vascular smooth muscle cell proliferation measurement · score 0.23
- sex hormone-binding globulin measurement · score 0.18
- urate measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P51959-F1 | alphafold | PREDICTED | 85.83 | — |
Amino-acid sequence (295 residues)
MIEVLTTTDS QKLLHQLNAL LEQESRCQPK VCGLRLIESA HDNGLRMTAR LRDFEVKDLL SLTQFFGFDT ETFSLAVNLL DRFLSKMKVQ PKHLGCVGLS CFYLAVKSIE EERNVPLATD LIRISQYRFT VSDLMRMEKI VLEKVCWKVK ATTAFQFLQL YYSLLQENLP LERRNSINFE RLEAQLKACH CRIIFSKAKP SVLALSIIAL EIQAQKCVEL TEGIECLQKH SKINGRDLTF WQELVSKCLT EYSSNKCSKP NVQKLKWIVS GRTARQLKHS YYRITHLPTI PEMVP
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