About 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 (FUT6) is a protein
from Homo sapiens identified by UniProt accession
P51993, 359 residues long.
MolForge cross-references it against 0 known binders and
96 disease associations.
Target properties
| Protein name | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 |
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| UniProt accession | P51993 |
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| Gene | FUT6 |
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| Organism | Homo sapiens |
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| Length | 359 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (96)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.38
- blood protein measurement · score 0.37
- aspartate aminotransferase measurement · score 0.35
- N-glycan measurement · score 0.34
- e-selectin measurement · score 0.32
- basophil count · score 0.32
- cancer biomarker measurement · score 0.31
- serum gamma-glutamyl transferase measurement · score 0.30
- mosquito bite reaction itch intensity measurement · score 0.30
- vitamin B12 measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P51993-F1 | alphafold | PREDICTED | 89.31 | — |
Amino-acid sequence (359 residues)
MDPLGPAKPQ WSWRCCLTTL LFQLLMAVCF FSYLRVSQDD PTVYPNGSRF PDSTGTPAHS IPLILLWTWP FNKPIALPRC SEMVPGTADC NITADRKVYP QADAVIVHHR EVMYNPSAQL PRSPRRQGQR WIWFSMESPS HCWQLKAMDG YFNLTMSYRS DSDIFTPYGW LEPWSGQPAH PPLNLSAKTE LVAWAVSNWG PNSARVRYYQ SLQAHLKVDV YGRSHKPLPQ GTMMETLSRY KFYLAFENSL HPDYITEKLW RNALEAWAVP VVLGPSRSNY ERFLPPDAFI HVDDFQSPKD LARYLQELDK DHARYLSYFR WRETLRPRSF SWALAFCKAC WKLQEESRYQ TRGIAAWFT
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