Zinc finger protein 136 (ZNF136)

About Zinc finger protein 136

Zinc finger protein 136 (ZNF136) is a protein from Homo sapiens identified by UniProt accession P52737, 540 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Zinc finger protein 136
UniProt accession	P52737
Gene	ZNF136
Organism	Homo sapiens
Length	540 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

pancreatic adenocarcinoma · score 0.14
prostate carcinoma · score 0.11
Familial prostate cancer · score 0.11
prostate cancer · score 0.11
chronic kidney disease · score 0.01
Pick disease · score 0.00
invasive breast ductal carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P52737-F1	alphafold	PREDICTED	74.60	—

Amino-acid sequence (540 residues)

MDSVAFEDVD VNFTQEEWAL LDPSQKNLYR DVMWETMRNL ASIGKKWKDQ NIKDHYKHRG RNLRSHMLER LYQTKDGSQR GGIFSQFANQ NLSKKIPGVK LCESIVYGEV SMGQSSLNRH IKDHSGHEPK EYQEYGEKPD TRNQCWKPFS SHHSFRTHEI IHTGEKLYDC KECGKTFFSL KRIRRHIITH SGYTPYKCKV CGKAFDYPSR FRTHERSHTG EKPYECQECG KAFTCITSVR RHMIKHTGDG PYKCKVCGKP FHSLSSFQVH ERIHTGEKPF KCKQCGKAFS CSPTLRIHER THTGEKPYEC KQCGKAFSYL PSLRLHERIH TGEKPFVCKQ CGKAFRSAST FQIHERTHTG EKPYECKECG EAFSCIPSMR RHMIKHTGEG PYKCKVCGKP FHSLSPFRIH ERTHTGEKPY VCKHCGKAFV SSTSIRIHER THTGEKPYEC KQCGKAFSYL NSFRTHEMIH TGEKPFECKR CGKAFRSSSS FRLHERTHTG QKPYHCKECG KAYSCRASFQ RHMLTHAEDG PPYKCMWESL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards