Zinc finger protein 140 (ZNF140)

About Zinc finger protein 140

Zinc finger protein 140 (ZNF140) is a protein from Homo sapiens identified by UniProt accession P52738, 457 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Zinc finger protein 140
UniProt accession	P52738
Gene	ZNF140
Organism	Homo sapiens
Length	457 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

BMI-adjusted waist-hip ratio · score 0.17
cortical thickness · score 0.17
pancreatic adenocarcinoma · score 0.14
brain measurement · score 0.14
cortical surface area measurement · score 0.14
intraocular pressure measurement · score 0.14
cardiovascular disease · score 0.08
waist-hip ratio · score 0.07
hypertension · score 0.07
Abnormality of refraction · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P52738-F1	alphafold	PREDICTED	68.72	—

Amino-acid sequence (457 residues)

MSQGSVTFRD VAIDFSQEEW KWLQPAQRDL YRCVMLENYG HLVSLGLSIS KPDVVSLLEQ GKEPWLGKRE VKRDLFSVSE SSGEIKDFSP KNVIYDDSSQ YLIMERILSQ GPVYSSFKGG WKCKDHTEML QENQGCIRKV TVSHQEALAQ HMNISTVERP YGCHECGKTF GRRFSLVLHQ RTHTGEKPYA CKECGKTFSQ ISNLVKHQMI HTGKKPHECK DCNKTFSYLS FLIEHQRTHT GEKPYECTEC GKAFSRASNL TRHQRIHIGK KQYICRKCGK AFSSGSELIR HQITHTGEKP YECIECGKAF RRFSHLTRHQ SIHTTKTPYE CNECRKAFRC HSFLIKHQRI HAGEKLYECD ECGKVFTWHA SLIQHTKSHT GEKPYACAEC DKAFSRSFSL ILHQRTHTGE KPYVCKVCNK SFSWSSNLAK HQRTHTLDNP YEYENSFNYH SFLTEHQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards