About Zinc finger protein 131
Zinc finger protein 131 (ZNF131) is a protein
from Homo sapiens identified by UniProt accession
P52739, 623 residues long.
MolForge cross-references it against 0 known binders and
47 disease associations.
Target properties
| Protein name | Zinc finger protein 131 |
|---|
| UniProt accession | P52739 |
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| Gene | ZNF131 |
|---|
| Organism | Homo sapiens |
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| Length | 623 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (47)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- body mass index · score 0.29
- lean body mass · score 0.27
- mean corpuscular hemoglobin concentration · score 0.27
- Immature Reticulocyte Fraction Measurement · score 0.26
- fat body mass · score 0.25
- age at menarche · score 0.25
- smoking status measurement · score 0.24
- body fat percentage · score 0.22
- reticulocyte count · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P52739-F1 | alphafold | PREDICTED | 52.65 | — |
Amino-acid sequence (623 residues)
MEAEETMECL QEFPEHHKMI LDRLNEQREQ DRFTDITLIV DGHHFKAHKA VLAACSKFFY KFFQEFTQEP LVEIEGVSKM AFRHLIEFTY TAKLMIQGEE EANDVWKAAE FLQMLEAIKA LEVRNKENSA PLEENTTGKN EAKKRKIAET SNVITESLPS AESEPVEIEV EIAEGTIEVE DEGIETLEEV ASAKQSVKYI QSTGSSDDSA LALLADITSK YRQGDRKGQI KEDGCPSDPT SKQVEGIEIV ELQLSHVKDL FHCEKCNRSF KLFYHFKEHM KSHSTESFKC EICNKRYLRE SAWKQHLNCY HLEEGGVSKK QRTGKKIHVC QYCEKQFDHF GHFKEHLRKH TGEKPFECPN CHERFARNST LKCHLTACQT GVGAKKGRKK LYECQVCNSV FNSWDQFKDH LVIHTGDKPN HCTLCDLWFM QGNELRRHLS DAHNISERLV TEEVLSVETR VQTEPVTSMT IIEQVGKVHV LPLLQVQVDS AQVTVEQVHP DLLQDSQVHD SHMSELPEQV QVSYLEVGRI QTEEGTEVHV EELHVERVNQ MPVEVQTELL EADLDHVTPE IMNQEERESS QADAAEAARE DHEDAEDLET KPTVDSEAEK AENEDRTALP VLE
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