About Zinc finger protein 132
Zinc finger protein 132 (ZNF132) is a protein
from Homo sapiens identified by UniProt accession
P52740, 706 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Zinc finger protein 132 |
|---|
| UniProt accession | P52740 |
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| Gene | ZNF132 |
|---|
| Organism | Homo sapiens |
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| Length | 706 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (32)
Diseases linked to this target (Open Targets).
- platelet count · score 0.34
- neurodegenerative disease · score 0.32
- platelet crit · score 0.24
- mean platelet volume · score 0.18
- platelet component distribution width · score 0.11
- mean corpuscular volume · score 0.11
- age at menarche · score 0.10
- puberty onset measurement · score 0.09
- breast cancer · score 0.08
- neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P52740-F1 | alphafold | PREDICTED | 68.02 | — |
Amino-acid sequence (706 residues)
MALPSPQVLM GLPALLMGPA QHTSWPCGSA VPTLKSMVTF EDVAVYFSQE EWELLDAAQR HLYHSVMLEN LELVTSLGSW HGVEGEGAHP KQNVSVEVLQ VRIPNADPST KKANSCDMCG PFLKDILHLA EHQGTQSEEK PYTCGACGRD FWLNANLHQH QKEHSGGKPF RWYKDRDALM KSSKVHLSEN PFTCREGGKV ILGSCDLLQL QAVDSGQKPY SNLGQLPEVC TTQKLFECSN CGKAFLKSST LPNHLRTHSE EIPFTCPTGG NFLEEKSILG NKKFHTGEIP HVCKECGKAF SHSSKLRKHQ KFHTEVKYYE CIACGKTFNH KLTFVHHQRI HSGERPYECD ECGKAFSNRS HLIRHEKVHT GERPFECLKC GRAFSQSSNF LRHQKVHTQV RPYECSQCGK SFSRSSALIQ HWRVHTGERP YECSECGRAF NNNSNLAQHQ KVHTGERPFE CSECGRDFSQ SSHLLRHQKV HTGERPFECC DCGKAFSNSS TLIQHQKVHT GQRPYECSEC RKSFSRSSSL IQHWRIHTGE KPYECSECGK AFAHSSTLIE HWRVHTKERP YECNECGKFF SQNSILIKHQ KVHTGEKPYK CSECGKFFSR KSSLICHWRV HTGERPYECS ECGRAFSSNS HLVRHQRVHT QERPYECIQC GKAFSERSTL VRHQKVHTRE RTYECSQCGK LFSHLCNLAQ HKKIHT
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