Zinc finger protein 134 (ZNF134)

About Zinc finger protein 134

Zinc finger protein 134 (ZNF134) is a protein from Homo sapiens identified by UniProt accession P52741, 427 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Zinc finger protein 134
UniProt accession	P52741
Gene	ZNF134
Organism	Homo sapiens
Length	427 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

Mastocytosis · score 0.25
Red cell distribution width · score 0.04
platelet component distribution width · score 0.02
diffuse large B-cell lymphoma · score 0.01
microphthalmia with limb anomalies · score 0.01
oral squamous cell carcinoma · score 0.00
osteoarthritis · score 0.00
activated PI3K-delta syndrome · score 0.00
type 2 diabetes mellitus · score 0.00
breast carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P52741-F1	alphafold	PREDICTED	65.39	—

Amino-acid sequence (427 residues)

MTLVTAGGAW TGPGCWHEVK DEESSSEQSI SIAVSHVNTS KAGLPAQTAL PCDICGPILK DILHLDEHQG THHGLKLHTC GACGRQFWFS ANLHQYQKCY SIEQPLRRDK SEASIVKNCT VSKEPHPSEK PFTCKEEQKN FQATLGGCQQ KAIHSKRKTH RSTESGDAFH GEQMHYKCSE CGKAFSRKDT LVQHQRIHSG EKPYECSECG KAFSRKATLV QHQRIHTGER PYECSECGKT FSRKDNLTQH KRIHTGEMPY KCNECGKYFS HHSNLIVHQR VHNGARPYKC SDCGKVFRHK STLVQHESIH TGENPYDCSD CGKSFGHKYT LIKHQRIHTE SKPFECIECG KFFSRSSDYI AHQRVHTGER PFVCSKCGKD FIRTSHLVRH QRVHTGERPY ECSECGKAYS LSSHLNRHQK VHTAGRL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards