About Zinc finger protein 138
Zinc finger protein 138 (ZNF138) is a protein
from Homo sapiens identified by UniProt accession
P52744, 262 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Zinc finger protein 138 |
|---|
| UniProt accession | P52744 |
|---|
| Gene | ZNF138 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 262 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- white matter hyperintensity measurement · score 0.29
- hypertension · score 0.29
- protein measurement · score 0.08
- colorectal cancer · score 0.01
- Williams syndrome · score 0.00
- motor developmental delay due to 14q32.2 paternally expressed gene defect · score 0.00
- neoplasm · score 0.00
- prostate adenocarcinoma · score 0.00
- Central precocious puberty · score 0.00
- Beckwith-Wiedemann syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P52744-F1 | alphafold | PREDICTED | 68.76 | — |
Amino-acid sequence (262 residues)
MKRHEMVVAK HSALCSRFAQ DLWLEQNIKD SFQKVTLSRY GKYGHKNLQL RKGCKSVDEC KGHQGGFNGL NQCLKITTSK IFQCNKYVKV MHKFSNSNRH KIRHTENKHF RCKECDKSLC MLSRLTQHKK IHTRENFYKC EECGKTFNWS TNLSKPKKIH TGEKPYKCEV CGKAFHQSSI LTKHKIIRTG EKPYKCAHCG KAFKQSSHLT RHKIIHTEEK PYKCEQCGKV FKQSPTLTKH QIIYTGEEPY KCEECGKAFN LS
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