About Ephrin-A5
Ephrin-A5 (EFNA5) is a protein
from Homo sapiens identified by UniProt accession
P52803, 228 residues long.
MolForge cross-references it against 0 known binders and
187 disease associations.
Target properties
| Protein name | Ephrin-A5 |
|---|
| UniProt accession | P52803 |
|---|
| Gene | EFNA5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (187)
Diseases linked to this target (Open Targets).
- serum gamma-glutamyl transferase measurement · score 0.50
- self reported educational attainment · score 0.50
- serum alanine aminotransferase measurement · score 0.48
- insomnia measurement · score 0.48
- smoking status measurement · score 0.46
- mathematical ability · score 0.46
- cortical thickness · score 0.44
- attention deficit hyperactivity disorder · score 0.43
- antisocial behaviour measurement · score 0.43
- substance abuse · score 0.43
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P52803-F1 | alphafold | PREDICTED | 78.49 | — |
Amino-acid sequence (228 residues)
MLHVEMLTLV FLVLWMCVFS QDPGSKAVAD RYAVYWNSSN PRFQRGDYHI DVCINDYLDV FCPHYEDSVP EDKTERYVLY MVNFDGYSAC DHTSKGFKRW ECNRPHSPNG PLKFSEKFQL FTPFSLGFEF RPGREYFYIS SAIPDNGRRS CLKLKVFVRP TNSCMKTIGV HDRVFDVNDK VENSLEPADD TVHESAEPSR GENAAQTPRI PSRLLAILLF LLAMLLTL
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