About Cysteine-rich protein 2
Cysteine-rich protein 2 (CRIP2) is a protein
from Homo sapiens identified by UniProt accession
P52943, 208 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Cysteine-rich protein 2 |
|---|
| UniProt accession | P52943 |
|---|
| Gene | CRIP2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 208 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.18
- total blood protein measurement · score 0.11
- diabetes mellitus · score 0.11
- hypothyroidism · score 0.10
- gut microbiome measurement · score 0.10
- immunoglobulin isotype switching measurement · score 0.09
- systemic scleroderma · score 0.08
- endocrine system disease · score 0.08
- complement C1s subcomponent measurement · score 0.08
- serum albumin measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P52943-F1 | alphafold | PREDICTED | 72.92 | — |
Amino-acid sequence (208 residues)
MASKCPKCDK TVYFAEKVSS LGKDWHKFCL KCERCSKTLT PGGHAEHDGK PFCHKPCYAT LFGPKGVNIG GAGSYIYEKP LAEGPQVTGP IEVPAARAEE RKASGPPKGP SRASSVTTFT GEPNTCPRCS KKVYFAEKVT SLGKDWHRPC LRCERCGKTL TPGGHAEHDG QPYCHKPCYG ILFGPKGVNT GAVGSYIYDR DPEGKVQP
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