About Nudix hydrolase 6
Nudix hydrolase 6 (NUDT6) is a protein
from Homo sapiens identified by UniProt accession
P53370, 316 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | Nudix hydrolase 6 |
|---|
| UniProt accession | P53370 |
|---|
| Gene | NUDT6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 316 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (53)
Diseases linked to this target (Open Targets).
- body height · score 0.41
- neurodegenerative disease · score 0.40
- appendicular lean mass · score 0.35
- lean body mass · score 0.29
- body weight · score 0.27
- vital capacity · score 0.22
- BMI-adjusted waist-hip ratio · score 0.21
- type 2 diabetes mellitus · score 0.18
- fat body mass · score 0.17
- waist-hip ratio · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P53370-F1 | alphafold | PREDICTED | 86.68 | — |
Amino-acid sequence (316 residues)
MRQPLSWGRW RAMLARTYGP GPSAGYRWAS GAQGYVRNPP VGACDLQGEL DRFGGISVRL ARLDALDRLD AAAFQKGLQA AVQQWRSEGR TAVWLHIPIL QSRFIAPAAS LGFCFHHAES DSSTLTLWLR EGPSRLPGYA SHQVGVAGAV FDESTRKILV VQDRNKLKNM WKFPGGLSEP EEDIGDTAVR EVFEETGIKS EFRSVLSIRQ QHTNPGAFGK SDMYIICRLK PYSFTINFCQ EECLRCEWMD LNDLAKTENT TPITSRVARL LLYGYREGFD KIDLTVEELP AVYTGLFYKL YHKELPENYK TMKGID
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