Cytosolic Fe-S cluster assembly factor NUBP1 (NUBP1)

About Cytosolic Fe-S cluster assembly factor NUBP1

Cytosolic Fe-S cluster assembly factor NUBP1 (NUBP1) is a protein from Homo sapiens identified by UniProt accession P53384, 320 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.

Target properties

Protein name	Cytosolic Fe-S cluster assembly factor NUBP1
UniProt accession	P53384
Gene	NUBP1
Organism	Homo sapiens
Length	320 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (82)

Diseases linked to this target (Open Targets).

aspartate aminotransferase measurement · score 0.31
blood protein measurement · score 0.11
neurodegenerative disease · score 0.08
syndactyly type 1 · score 0.08
syndactyly type 4 · score 0.07
Syndactyly type 2 · score 0.07
colorectal carcinoma · score 0.07
syndactyly type 3 · score 0.07
Split hand-split foot malformation · score 0.07
syndactyly type 5 · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P53384-F1	alphafold	PREDICTED	89.68	—

Amino-acid sequence (320 residues)

MEEVPHDCPG ADSAQAGRGA SCQGCPNQRL CASGAGATPD TAIEEIKEKM KTVKHKILVL SGKGGVGKST FSAHLAHGLA EDENTQIALL DIDICGPSIP KIMGLEGEQV HQSGSGWSPV YVEDNLGVMS VGFLLSSPDD AVIWRGPKKN GMIKQFLRDV DWGEVDYLIV DTPPGTSDEH LSVVRYLATA HIDGAVIITT PQEVSLQDVR KEINFCRKVK LPIIGVVENM SGFICPKCKK ESQIFPPTTG GAELMCQDLE VPLLGRVPLD PLIGKNCDKG QSFFIDAPDS PATLAYRSII QRIQEFCNLH QSKEENLISS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards