Geranylgeranyl transferase type-2 subunit beta (RABGGTB)

About Geranylgeranyl transferase type-2 subunit beta

Geranylgeranyl transferase type-2 subunit beta (RABGGTB) is a protein from Homo sapiens identified by UniProt accession P53611, 331 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	Geranylgeranyl transferase type-2 subunit beta
UniProt accession	P53611
Gene	RABGGTB
Organism	Homo sapiens
Length	331 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P53611-F1	alphafold	PREDICTED	96.70	—

Amino-acid sequence (331 residues)

MGTPQKDVII KSDAPDTLLL EKHADYIASY GSKKDDYEYC MSEYLRMSGI YWGLTVMDLM GQLHRMNREE ILAFIKSCQH ECGGISASIG HDPHLLYTLS AVQILTLYDS INVIDVNKVV EYVKGLQKED GSFAGDIWGE IDTRFSFCAV ATLALLGKLD AINVEKAIEF VLSCMNFDGG FGCRPGSESH AGQIYCCTGF LAITSQLHQV NSDLLGWWLC ERQLPSGGLN GRPEKLPDVC YSWWVLASLK IIGRLHWIDR EKLRNFILAC QDEETGGFAD RPGDMVDPFH TLFGIAGLSL LGEEQIKPVN PVFCMPEEVL QRVNVQPELV S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards