About Myomesin-2
Myomesin-2 (MYOM2) is a protein
from Homo sapiens identified by UniProt accession
P54296, 1465 residues long.
MolForge cross-references it against 0 known binders and
319 disease associations.
Target properties
| Protein name | Myomesin-2 |
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| UniProt accession | P54296 |
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| Gene | MYOM2 |
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| Organism | Homo sapiens |
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| Length | 1465 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (319)
Diseases linked to this target (Open Targets).
- plasminogen activator inhibitor 1 measurement · score 0.30
- Alzheimer disease · score 0.30
- lysosomal storage disease · score 0.30
- multiple sclerosis · score 0.30
- Parkinson disease · score 0.30
- neurodegenerative disease · score 0.30
- PHF-tau measurement · score 0.20
- Abnormality of refraction · score 0.15
- neurofibrillary tangles measurement · score 0.15
- Flexion contracture · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P54296-F1 | alphafold | PREDICTED | 77.16 | — |
Amino-acid sequence (1465 residues)
MSLVTVPFYQ KRHRHFDQSY RNIQTRYLLD EYASKKRAST QASSQKSLSQ RSSSQRASSQ TSLGGTICRV CAKRVSTQED EEQENRSRYQ SLVAAYGEAK RQRFLSELAH LEEDVHLARS QARDKLDKYA IQQMMEDKLA WERHTFEERI SRAPEILVRL RSHTVWERMS VKLCFTVQGF PTPVVQWYKD GSLICQAAEP GKYRIESNYG VHTLEINRAD FDDTATYSAV ATNAHGQVST NAAVVVRRFR GDEEPFRSVG LPIGLPLSSM IPYTHFDVQF LEKFGVTFRR EGETVTLKCT MLVTPDLKRV QPRAEWYRDD VLLKESKWTK MFFGEGQASL SFSHLHKDDE GLYTLRIVSR GGVSDHSAFL FVRDADPLVT GAPGAPMDLQ CHDANRDYVI VTWKPPNTTT ESPVMGYFVD RCEVGTNNWV QCNDAPVKIC KYPVTGLFEG RSYIFRVRAV NSAGISRPSR VSDAVAALDP LDLRRLQAVH LEGEKEIAIY QDDLEGDAQV PGPPTGVHAS EISRNYVVLS WEPPTPRGKD PLMYFIEKSV VGSGSWQRVN AQTAVRSPRY AVFDLMEGKS YVFRVLSANR HGLSEPSEIT SPIQAQDVTV VPSAPGRVLA SRNTKTSVVV QWDRPKHEED LLGYYVDCCV AGTNLWEPCN HKPIGYNRFV VHGLTTGEQY IFRVKAVNAV GMSENSQESD VIKVQAALTV PSHPYGITLL NCDGHSMTLG WKVPKFSGGS PILGYYLDKR EVHHKNWHEV NSSPSKPTIL TVDGLTEGSL YEFKIAAVNL AGIGEPSDPS EHFKCEAWTM PEPGPAYDLT FCEVRDTSLV MLWKAPVYSG SSPVSGYFVD FREEDAGEWI TVNQTTTASR YLKVSDLQQG KTYVFRVRAV NANGVGKPSD TSEPVLVEAR PGTKEISAGV DEQGNIYLGF DCQEMTDASQ FTWCKSYEEI SDDERFKIET VGDHSKLYLK NPDKEDLGTY SVSVSDTDGV SSSFVLDPEE LERLMALSNE IKNPTIPLKS ELAYEIFDKG RVRFWLQAEH LSPDASYRFI INDREVSDSE IHRIKCDKAT GIIEMVMDRF SIENEGTYTV QIHDGKAKSQ SSLVLIGDAF KTVLEEAEFQ RKEFLRKQGP HFAEYLHWDV TEECEVRLVC KVANTKKETV FKWLKDDVLY ETETLPNLER GICELLIPKL SKKDHGEYKA TLKDDRGQDV SILEIAGKVY DDMILAMSRV CGKSASPLKV LCTPEGIRLQ CFMKYFTDEM KVNWCHKDAK ISSSEHMRIG GSEEMAWLQI CEPTEKDKGK YTFEIFDGKD NHQRSLDLSG QAFDEAFAEF QQFKAAAFAE KNRGRLIGGL PDVVTIMEGK TLNLTCTVFG NPDPEVIWFK NDQDIQLSEH FSVKVEQAKY VSMTIKGVTS EDSGKYSINI KNKYGGEKID VTVSVYKHGE KIPDMAPPQQ AKPKLIPASA SAAGQ
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