About Ornithine decarboxylase antizyme 1
Ornithine decarboxylase antizyme 1 (OAZ1) is a protein
from Homo sapiens identified by UniProt accession
P54368, 228 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Ornithine decarboxylase antizyme 1 |
|---|
| UniProt accession | P54368 |
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| Gene | OAZ1 |
|---|
| Organism | Homo sapiens |
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| Length | 228 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (33)
Diseases linked to this target (Open Targets).
- myeloid white cell count · score 0.07
- non-small cell lung carcinoma · score 0.05
- leukocyte count · score 0.02
- neoplasm · score 0.02
- viral disease · score 0.02
- chronic myelogenous leukemia · score 0.02
- oral squamous cell carcinoma · score 0.01
- cancer · score 0.01
- acute myeloid leukemia · score 0.01
- neuroblastoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P54368-F1 | alphafold | PREDICTED | 73.96 | — |
Amino-acid sequence (228 residues)
MVKSSLQRIL NSHCFAREKE GDKPSATIHA SRTMPLLSLH SRGGSSSESS RVSLHCCSNP GPGPRWCSDA PHPPLKIPGG RGNSQRDHNL SANLFYSDDR LNVTEELTSN DKTRILNVQS RLTDAKRINW RTVLSGGSLY IEIPGGALPE GSKDSFAVLL EFAEEQLRAD HVFICFHKNR EDRAALLRTF SFLGFEIVRP GHPLVPKRPD ACFMAYTFER ESSGEEEE
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