About Sodium/potassium-transporting ATPase subunit beta-3
Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3) is a protein
from Homo sapiens identified by UniProt accession
P54709, 279 residues long.
MolForge cross-references it against 0 known binders and
111 disease associations.
Target properties
| Protein name | Sodium/potassium-transporting ATPase subunit beta-3 |
|---|
| UniProt accession | P54709 |
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| Gene | ATP1B3 |
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| Organism | Homo sapiens |
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| Length | 279 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (111)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.43
- hair color · score 0.36
- leukocyte count · score 0.33
- mean corpuscular hemoglobin · score 0.32
- lymphocyte count · score 0.32
- brain measurement · score 0.32
- neuroimaging measurement · score 0.31
- IGF-1 measurement · score 0.28
- hair colour measurement · score 0.27
- brain volume measurement · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P54709-F1 | alphafold | PREDICTED | 89.66 | — |
Amino-acid sequence (279 residues)
MTKNEKKSLN QSLAEWKLFI YNPTTGEFLG RTAKSWGLIL LFYLVFYGFL AALFSFTMWV MLQTLNDEVP KYRDQIPSPG LMVFPKPVTA LEYTFSRSDP TSYAGYIEDL KKFLKPYTLE EQKNLTVCPD GALFEQKGPV YVACQFPISL LQACSGMNDP DFGYSQGNPC ILVKMNRIIG LKPEGVPRID CVSKNEDIPN VAVYPHNGMI DLKYFPYYGK KLHVGYLQPL VAVQVSFAPN NTGKEVTVEC KIDGSANLKS QDDRDKFLGR VMFKITARA
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