About Epithelial membrane protein 1
Epithelial membrane protein 1 (EMP1) is a protein
from Homo sapiens identified by UniProt accession
P54849, 157 residues long.
MolForge cross-references it against 0 known binders and
186 disease associations.
Target properties
| Protein name | Epithelial membrane protein 1 |
|---|
| UniProt accession | P54849 |
|---|
| Gene | EMP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 157 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (186)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.42
- neurodegenerative disease · score 0.40
- bone quantitative ultrasound measurement · score 0.36
- self reported educational attainment · score 0.33
- cholelithiasis · score 0.27
- lifestyle measurement · score 0.24
- C-reactive protein measurement · score 0.24
- bone density · score 0.23
- mathematical ability · score 0.22
- neurofibrillary tangles measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P54849-F1 | alphafold | PREDICTED | 90.66 | — |
Amino-acid sequence (157 residues)
MLVLLAGIFV VHIATVIMLF VSTIANVWLV SNTVDASVGL WKNCTNISCS DSLSYASEDA LKTVQAFMIL SIIFCVIALL VFVFQLFTME KGNRFFLSGA TTLVCWLCIL VGVSIYTSHY ANRDGTQYHH GYSYILGWIC FCFSFIIGVL YLVLRKK
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