About Epithelial membrane protein 2
Epithelial membrane protein 2 (EMP2) is a protein
from Homo sapiens identified by UniProt accession
P54851, 167 residues long.
MolForge cross-references it against 0 known binders and
124 disease associations.
Target properties
| Protein name | Epithelial membrane protein 2 |
|---|
| UniProt accession | P54851 |
|---|
| Gene | EMP2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 167 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (124)
Diseases linked to this target (Open Targets).
- nephrotic syndrome · score 0.62
- erythrocyte count · score 0.43
- facial asymmetry measurement · score 0.40
- heel bone mineral density · score 0.40
- familial idiopathic steroid-resistant nephrotic syndrome · score 0.37
- hemoglobin measurement · score 0.34
- hematocrit · score 0.33
- response to statin · score 0.33
- serum gamma-glutamyl transferase measurement · score 0.32
- neurodegenerative disease · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P54851-F1 | alphafold | PREDICTED | 95.03 | — |
Amino-acid sequence (167 residues)
MLVLLAFIIA FHITSAALLF IATVDNAWWV GDEFFADVWR ICTNNTNCTV INDSFQEYST LQAVQATMIL STILCCIAFF IFVLQLFRLK QGERFVLTSI IQLMSCLCVM IAASIYTDRR EDIHDKNAKF YPVTREGSYG YSYILAWVAF ACTFISGMMY LILRKRK
Explore Epithelial membrane protein 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets